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Claudia M d'Avila-Levy Selected Research

calpain inhibitors

2/2022Antileishmanial Efficacy of the Calpain Inhibitor MDL28170 in Combination with Amphotericin B.
1/2014The calpain inhibitor MDL28170 induces the expression of apoptotic markers in Leishmania amazonensis promastigotes.
7/2010Effects of the calpain inhibitor MDL28170 on the clinically relevant forms of Trypanosoma cruzi in vitro.
8/2006Antileishmanial activity of MDL 28170, a potent calpain inhibitor.

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Claudia M d'Avila-Levy Research Topics

Disease

5Infections
01/2021 - 01/2009
5Chagas Disease (American Trypanosomiasis)
01/2021 - 06/2012
3Leishmaniasis
02/2022 - 02/2013
2Parasitic Diseases (Parasitic Disease)
10/2016 - 08/2006
2Blister (Bulla)
01/2014 - 01/2006
1Coinfection
08/2018
1Lipid Metabolism Disorders (Metabolism Disorders, Lipid)
08/2018
1Acquired Immunodeficiency Syndrome (AIDS)
08/2018
1Wounds and Injuries (Trauma)
08/2018
1Opportunistic Infections (Opportunistic Infection)
01/2017

Drug/Important Bio-Agent (IBA)

5Peptide Hydrolases (Proteases)FDA Link
01/2021 - 08/2006
5Protease Inhibitors (Protease Inhibitor)IBA
08/2018 - 01/2009
4calpain inhibitorsIBA
02/2022 - 08/2006
3LopinavirFDA Link
01/2019 - 12/2016
2calpain inhibitor IIIIBA
02/2022 - 07/2010
2Pharmaceutical PreparationsIBA
11/2018 - 07/2010
2Nelfinavir (Viracept)FDA Link
08/2018 - 12/2016
1Drug CombinationsIBA
02/2022
1cruzipainIBA
01/2021
1Cysteine (L-Cysteine)FDA Link
01/2021
1Proteins (Proteins, Gene)FDA Link
01/2021
1Virulence Factors (Pathogenicity Factors)IBA
01/2021
1miltefosine (Impavido)IBA
01/2019
1benzonidazole (benznidazole)IBA
11/2018
1Oxidoreductases (Dehydrogenase)IBA
08/2018
1DNA (Deoxyribonucleic Acid)IBA
08/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2018
1Biomarkers (Surrogate Marker)IBA
08/2017
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2016
1Leucyl Aminopeptidase (Peptidase S)IBA
10/2016
1ChromatinIBA
01/2014
1pepstatin (pepstatin A)IBA
06/2012
1AntipainIBA
01/2006
1leupeptinIBA
01/2006

Therapy/Procedure

3Drug Therapy (Chemotherapy)
02/2022 - 01/2014
2Therapeutics
01/2019 - 08/2018